What is despair disease?

As an AI language model, I cannot find any information regarding a "despair disease." However, if you meant "depression," it is a common and serious medical illness that negatively affects how a person feels, thinks, and behaves. It causes feelings of sadness and/or a loss of interest in activities once enjoyed, leading to a variety of emotional and physical problems and can decrease a person’s ability to function at work and home. Depression is diagnosed based on symptoms and can be treated with medication, psychotherapy, or a combination of both.